Endocrinology
GE Healthcare, a division of General Electric Company (NYSE:GE) announced that Beloit Memorial Hospital, Beloit, Wis., has selected an Optima® XR640 digital radiographic system for its expanded emergency department.
The AAMC (Association of American Medical Colleges) applauds Rep. Allyson Schwartz (D-Pa.) for introducing legislation (H.R. 3134) to establish pilot "health care innovation zones" (HIZs) building on the strengths of academic medical centers (AMCs). The legislation creates and tests these zones around the country with the goal of improving patient outcomes, while slowing the growth of health care costs.
Bayer Diabetes Care in the UK and Ireland today unveils "DIDGET(TM), the
Senate Finance Committee Chair Max Baucus (D-Mont.) and ranking member Chuck Grassley (R-Iowa) on Monday released a 41-page document outlining policy options for financing health care reform, The Hill reports (Young, The Hill, 5/18). The paper is the third and final to be released before the senators draft health reform legislation. The document says Baucus and Grassley do not support all the proposals included in the paper, but does not indicate which are backed by the senators (Wayne, CQ Today, 5/18). The options, which will be discussed at a closed-door committee meeting on Wednesday, include a number of proposed spending cuts and new or revised taxes (Drucker, Roll Call, 5/18). The report outlines several ways to gain revenue by re-evaluating the tax exemption for employer-sponsored health care benefits, which cost the government $194.2 billion in revenue in 2008, according to the report. The options include:
Bayer Schering Pharma
Teva Pharmaceutical Industries Ltd. (NASDAQ: TEVA) announced that the U.S. Food and Drug Administration (FDA) has approved its New Drug Application (NDA) for Plan B® One-Step emergency contraception (levonorgestrel tablet, 1.5 mg). Now, with new Plan B® One-Step, women can help prevent an unintended pregnancy after unprotected sex or contraceptive failure with just one pill in one dose. The FDA is expanding over-the-counter (OTC) access to Plan B® One-Step for consumers age 17 or older; women younger than age 17 will require a prescription. The product will be available at licensed U.S. retail pharmacies within the next month.
The Department of Health and Human Services (DHHS) will hold six public hearings July 16, 2009. These hearings will take place in Lincoln at the State Office Building, 301 Centennial Mall South, lower level conference room A. The hearings are being held to accept comments on proposed regulations.
Boston Scientific Corporation (NYSE: BSX) announced CE Mark for its LATITUDE® Patient Management system. The LATITUDE system remotely monitors patients with implantable cardiac devices, gathering information on both the device and a patient"s heart health status. The system can also detect clinical events between scheduled physician visits and send relevant data directly to a patient"s physician. It will be launched in Europe in a phased approach beginning this week.
The IMPACT (Important Perspectives on Alzheimer"s Care & Treatment) study explored the views of 1800 people - physicians (GPs and specialists),1 Alzheimer"s carers,1 payors1 and the general public1 in France, Germany, Italy, Spain and the UK
Caesarean sections -- which are performed in 31% of births, up from 4.5% in 1965 -- often are considered an unnecessary risk and "an example of how the intensive and expensive U.S. brand of medicine has failed to deliver better results and may, in fact, be doing more harm than good," the Los Angeles Times reports. According to the Times, c-sections can increase a woman"s risk of complications, such as infection, blood clots and premature delivery. Even without complication, c-sections typically result in longer hospital stays and increased costs. Expenses related to c-section births account for 45% of the more than $79 billion in annual hospital charges that childbirth incurs in the U.S. annually. The average uncomplicated c-section costs about $4,500, which is about twice the cost for vaginal births. C-sections cost about $13,000 for privately insured patients. According to a 2008 report by Childbirth Connection, "The financial toll of maternity care on private (insurers)/employers and Medicaid/taxpayers is especially large." It also said, "Maternity care thus plays a considerable role in escalating health care costs, which increasingly threaten the financial stability of families, employers, and federal and state budgets." Addressing the Increase
Though discoveries about Alzheimer"s disease risk factors are often in the news, adults do not know about the relationship between Alzheimer"s disease risk and heart health, nor that physical activity can be protective against dementia, according to new research reported today at the Alzheimer"s Association 2009 International Conference on Alzheimer"s Disease (ICAD 2009) in Vienna.
Simulating medical scenarios helps medical students learn and retain vital information, according to a new study done by researchers at Wake Forest University School of Medicine.
A National e-health record promises to ensure patients have access to more expedient
Trying to get fit but can"t work it into your daily schedule? Incorporating even relatively short bouts of exercise into a daily commute appears to deliver significant rewards, according to a new study from the University of North Carolina at Chapel Hill.
In a speech before the Ghanaian Parliament, President Obama on Saturday reiterated U.S. support for public health programs that will reduce maternal mortality and the spread of HIV/AIDS in Africa, the New York Times reports. The speech, which was televised across the continent, focused on international relations with Africa and empowering African nations to address problems (Baker, New York Times, 7/12).In a portion of the speech about strengthening public health, Obama said that there has been "enormous progress ... in parts of Africa" in recent years. He continued, "Far more people are living productively with HIV/AIDS, and getting the drugs they need. But too many still die from diseases that shouldn"t kill them." He added, "When children are being killed because of a mosquito bite, and mothers are dying in childbirth, then we know that more progress must be made." Obama said that "incentives often provided by donor nations" often compel doctors and nurses to "go overseas, or work for programs that focus on a single disease," which "creates gaps in primary care and basic prevention." He also said that Africans must "make responsible choices that prevent the spread of disease, while promoting public health in their communities and countries."Obama noted that the U.S. has committed $63 billion "to meet these challenges." He added that the U.S. will not "confront illnesses in isolation" but instead "invest in public health systems that promote wellness and focus on the health of mothers and children" (AP/USA Today, 7/11). Obama also visited a women"s clinic to highlight U.S-backed programs to fight infant and maternal mortality (New York Times, 7/12).
The American Society of Hematology (ASH), the world"s largest professional society of blood specialists, will honor six scientists who have made significant contributions to the understanding of hematologic diseases. These awards, including the newly created Ernest Beutler Lecture and Prize, will be presented at the 51st ASH Annual Meeting taking place December 5-8 in New Orleans.
The Kansas City Star on Sunday examined a national petition -- signed recently by several local organizations -- requesting that CVS Caremark unlock condoms in all of its CVS pharmacy stores. "The petition, sponsored by the labor coalition Change to Win, said CVS stores tended to lock up condoms, especially in low-income neighborhoods with high numbers of minorities," the Star reports. CVS has said the practice is "a defense against shoplifters in stores where large numbers of condoms were stolen," according to the Star. CVS spokesperson Mike DeAngelis said not all condoms are locked in display cases. "DeAngelis also said the group behind the condom petition ò€¦ was mounting a smear campaign against CVS because of a labor dispute," the article states (Erickson, 7/12).
Needle exchange programs (NEPs) "are an inexpensive public health intervention, especially when compared with the social costs of treating individuals with HIV or hepatitis-related chronic liver disease," Maureen Trotter, a pathologist and president of the Taylor-Jones-Haskell County Medical Society, writes in the Abilene Reporter News. She adds that legislation introduced this year in the Texas Legislature "to allow public health departments and organizations to establish disease control programs that provide for the anonymous exchange of used hypodermic needles and syringes for sterile ones, offer education and substance abuse treatment and blood-borne disease testing" failed to come to a floor vote. Trotter further discusses NEPs, citing data on outcomes of NEPs, and writes, "The costs of preventing one case of HIV is estimated between $4,000 and $12,000 via NEPs. The medical cost of treating a person infected with HIV is about $200,000," adding, "These programs, if implemented, could save Texas millions of dollars" (7/12).
PARASITOLOGY: Immune protection against lethal parasitic disease
When cells experiencing DNA damage fail to repair themselves, they send a signal to their neighbors letting them know they"re in trouble. The discovery, which shows that a process dubbed the DDR (DNA Damage Response) also controls communication from cell to cell, has implications for both cancer and aging. The findings appear in the July 13 online edition of the Nature Cell Biology.
Patients with multiple sclerosis who smoke appear to experience a more rapid progression of their disease, according to a report in the July issue of Archives of Neurology, one of the JAMA/Archives journals.
Implantable lenses made of a collagen-like substance appear to provide stable correction of moderate to high nearsightedness (myopia) over four years of follow-up, according to a report in the July issue of Archives of Ophthalmology, one of the JAMA/Archives journals.
Research led by The University of Arizona College of Pharmacy has found that medication prescribers correctly identified fewer than half of drug pairs with potentially dangerous drug-drug interactions.
Approximately two-thirds of the 1.5 million Americans living with lupus will develop some type of skin disease. Lupus is an autoimmune disease in which the immune system is unbalanced causing it to become destructive to any organ and tissue in the body. Skin disease in lupus can cause rashes or sores (lesions), most of which will appear on sun-exposed areas, such as a person"s face, ears, neck, arms, and legs. In addition, 40-70 percent of people with systemic lupus will find that their disease is made worse by exposure to ultraviolet (UV) rays from sunlight or artificial light. For this and other reasons, people with lupus are advised to take steps to protect themselves from exposure to UV light.
AMAG Pharmaceuticals, Inc. (NASDAQ:AMAG) announced that Feraheme ™ (ferumoxytol) Injection is now available for commercial sale in the United States. Feraheme is an intravenous (IV) iron replacement therapy for the treatment of iron deficiency anemia in adult patients with chronic kidney disease. Feraheme can provide patients with a 1 gram therapeutic course of iron in two 510 mg IV injections administered as quickly as 17 seconds each, within one week. Feraheme was approved by the U.S. Food and Drug Administration on June 30, 2009.
New research from the Stanford University School of Medicine and Stanford Hospital & Clinics suggests that the use of a dietary supplement after Roux-en-Y gastric bypass surgery can help obese patients to more quickly lose weight and to avoid deficiency of a critical B vitamin.
What if you could test your risk for Alzheimer"s disease much like your cholesterol levels - through a simple blood test?
The tiny translucent egg nestled in the special laboratory gel was a mere 30 days old, but its four-week birthday caused researchers to quietly celebrate. This was the first time anyone had successfully grown a woman"s immature egg cells, contained in a tiny sac called a follicle, to a healthy and nearly mature egg in the laboratory. When an egg is fully mature, it is ready to be fertilized.
If that office inkjet printer has become just another fixture, it"s time to take a fresh look at it. Similar technology may soon be used to develop paper-based biosensors that can detect certain harmful toxins that can cause food poisoning or be used as bioterrorism agents.
In the brain, many types of synaptic proteins are spatio-temporally regulated to maintain synaptic activity at a constant level. Here, the Japanese research group led by Professor Masaki Fukata, Drs. Yuko Fukata and Jun Noritake in National Institute for Physiological Sciences, Japan, found that two types of palmitoylating enzymes finely-tune the location and function of a major synaptic protein, PSD-95, in different ways. They also found that this mechanism contributes to keeping synaptic activity stable when synaptic activity dynamically changes. The Japan Science and Technology Agency (JST) supported this study. They report the finding in Journal of Cell Biology published on July 13, 2009.
For people without a prior conviction for a hands-on sex offense, the consumption of child pornography alone does not, in itself, seem to represent a risk factor for committing such an offense. Researchers writing in the open access journal BMC Psychiatry studied 231 men convicted of consuming child pornography in 2002 and found that only 1% had gone on to commit a hands-on sex offense in the following six years.
NovImmune, an immunology-focused biotech company
A UQ Science researcher has received a prestigious honorary fellowship for her long-time work into understanding the underlying mechanisms of pain.
Thermo Fisher Scientific Inc., the world leader in serving science, announced it offers a premium collection of Thermo Scientific Taq DNA polymerases that are licensed and optimised for use in PCR processes. ThermoPrime Taq DNA Polymerase and Thermo-Start® Taq DNA Polymerase are designed to provide excellent amplification specificity and improved product yield. In addition, the high purity of these enzymes ensures their consistent and reliable performance.
New data show that Medicare beneficiaries registered to use My Health Manager, Kaiser Permanente"s personal health record, are overwhelmingly satisfied with using the Internet to manage their health care online. Results from the recent Kaiser Permanente survey examining Web site usage and Medicare beneficiary satisfaction were presented today at the World Health Care Congress" 5th Annual Leadership Summit on Medicare in Washington, D.C.
Researchers from the Kimmel Cancer Center at Jefferson have identified a protein relationship that may be an ideal treatment target for ER+ breast cancer. The study was reported in the July 15 issue of Cancer Research.
Researchers studying a large population of women in Denmark found that those who took hormone replacement therapy (HRT) after menopause
A new study has revealed a possible link between smoking and more rapid progression of disability in multiple sclerosis (MS).
Today, House Speaker Nancy Pelosi and Committee Chairmen Henry Waxman, Charlie Rangel, and George Miller introduced their unified health care reform bill. The following is the statement of Ron Pollack, Executive Director of Families USA, about this development:
"An unprecedented effort to computerize the nation"s hospitals and physician offices could be the key to reducing crippling health care costs - or a giveaway to technology vendors whose sales will be subsidized by taxpayers," the Dallas Morning News reports. The $45 billion, stimulus-funded effort in question could help reduce costs by cutting into the country"s $37.6 billion in medical errors each year, for instance. But, if requirements for providers seeking stimulus funding are too strict, the program could turn into "a bonanza for software vendors."
New research showing that "a receptor molecule involved in the recognition of HIV-1 responds to the virus differently in women than in men," might "explain why HIV infection progresses faster to AIDS in women than in men with similar viral loads," the HealthDay/Greenville Daily Reflector reports. The study was conducted by researchers at the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University and will be published in an upcoming issue of the journal Nature Medicine. Study authors also note that during the early stages of infection, women tend to have a stronger immune response to HIV than men, but then progress to AIDS more quickly. The different immune system response "then leads to differences in chronic T-cell activation, a known activator of disease progression, according to the researchers," the article states (7/13). Researcher Marcus Altfeld said the findings raise new questions about how sex hormones affect HIV in the body. "Focusing on immune activation separately from viral replication might give us new therapeutic approaches" to treating HIV, he added (AFP/Google News, 7/13).
"The heavy lifting" for garnering Congressional support for eliminating the federal ban on funding for needle exchange programs "was left to David Obey, the Democrat from Wisconsin who chairs both the House Appropriations Committee and the Subcommittee on Labor, Education, Health and Human Services," Boston Globe columnist Derrick Jackson writes in response to the introduction of legislation by the House Appropriations Committee last week that would lift the ban. Jackson also notes that while President Obama addressed needle exchange during the campaign, his FY 2010 budget continued the ban and that a "White House spokesmen said [President] Obama need[ed] time to "build support" with Congress and the public to get rid of the ban." In discussing the history behind the ban and the science supporting the use of needle exchange programs, Jackson says, "It is time, with the House having taken the lead, for [President] Obama to get out front and say once and for all that science takes the front seat to ideology," concluding, "Some issues are too critical to the very lives of Americans to wait to "build support"" (7/14).
ChemBioOffice 2010 is the latest release of CambridgeSoft Corporation"s full suite of integrated scientific desktop applications designed to aid individual chemists and biologists at their desktops, while also providing a shared solution benefiting scientists across an institution.
A new blood glucose monitor, unveiled today, connects directly to Nintendo DST and Nintendo DST Lite gaming systems and was designed specifically for children with diabetes.
Babies born to obese mothers may have an increased risk of asthma, according to data from a new study to be presented on May 19 at the 105th International Conference of the American Thoracic Society in San Diego.
To mark World Population Day on July 11, U.N. officials are calling for investment in women and girls during the global financial crisis as a way to promote economic recovery and tackle poverty and inequality, afrol News reports. "There is no smarter investment in troubled times," Thoraya Ahmed Obaid, executive director of UNFPA, said. According to Obaid, even before the financial downturn, women and girls were the majority of the world"s poor. "Now, they are falling deeper into poverty and face increased health risks, especially if they are pregnant," she said, adding that the "health gap" will get bigger "unless we increase social investments, maintain health gains and expand efforts to save more women"s lives."
The Senate Health, Education, Labor and Pensions Committee on Monday rejected several Republican abortion-related amendments to the committee" health overhaul bill but adopted a Democratic amendment allowing health care providers who oppose abortion to contract with health plans, CQ HealthBeat reports. The committee voted mostly along party lines to reject an amendment by Sen. Orrin Hatch (R-Utah) that would have prohibited abortion coverage in a health care exchange for participants who receive government-subsidized coverage. Democrats said that the language could have been used to restrict abortion coverage in private insurance plans. The amendment failed in an 11-12 vote, with Sen. Bob Casey (D-Pa.) crossing party lines to support it. The committee also voted 11-12 to reject an amendment by Sen. Tom Coburn (R-Okla.) that would have specified that federal health reform legislation could not override state laws on parental notification when minors seek abortion services. The committee adopted by voice vote an amendment submitted by Sen. Christopher Dodd (D-Conn.) on behalf of committee Chair Edward Kennedy (D-Mass.), who is battling brain cancer. The amendment states that health care providers could not be excluded from contracting with health plans taking part in a health insurance exchange on the basis that the provider performs abortions or refuses to perform abortions except in an emergency if "performing abortions is contrary to the religious or moral beliefs of the provider or entity." Sen. Mike Enzi (R-Wyo.) said that he is concerned the amendment might be unconstitutional because Congress cannot legislate on religious issues. Sen. Kay Hagan (D-N.C.) expressed concern that the phrase "except in emergency" was not more clearly defined. Dodd declined Enzi"s request to withdraw the amendment until it could be clarified. The committee rejected Coburn"s amendment that was a more sweeping version of "conscience" protections for health care providers with religious or moral objections (Norman [1], CQ HealthBeat, 7/13). Dodd said he expects the committee to complete its work on the bill Tuesday night (Norman [2], CQ HealthBeat, 7/13).According to NPR"s "Morning Edition," abortion is one of the most likely issues to "throw a wrench into the already fragile gears" of health reform legislation. Sen. Chuck Grassley (R-Iowa) said, "I take a view that there"s almost anything (that can be compromised) in public affairs except probably the issue of abortion." Nineteen House Democrats recently sent a letter to House Speaker Nancy Pelosi (D-Calif.), saying, "We cannot support any health care reform proposal unless it explicitly excludes abortion from the scope of any government-defined or subsidized health insurance plan." Democratic pollster Mark Mellman said any new restrictions on abortion coverage in government-subsidized health plans might be unpopular with the public. "Right now most health care plans cover abortion, cover contraception, cover women"s reproductive health," Mellman said. He added, "To some extent what they"re talking about on Capitol Hill is taking away coverage that people already have. Americans want health care reform. But they will oppose health care reform if it takes away the coverage they now have for things like abortion and contraception." Mellman recently conducted a poll for the National Women"s Law Center that found that 75% of respondents would prefer to have an independent commission of medical experts and citizens, rather than lawmakers, decide what should be covered (Rovner, "Morning Edition," NPR, 7/14).
A bill (HR 20, S 324) in Congress that would mandate funding for research, services and public education related to postpartum depression has sparked debate over whether all women should be screened for the condition, Time reports. The Melanie Blocker-Stokes Postpartum Depression Research and Care Act, also known as the Mothers Act, passed the House and is before the Senate. The bill does not specifically include funding for PPD testing, though an earlier version did; regardless, critics say it would still lead to greater screening. According to Time, the issue at the center of the debate is whether PPD screening identifies actual cases "or simply contribute[s] to the potentially dangerous medicalization of motherhood." Ingrid Johnston-Robledo, director of women"s studies at the State University of New York, said that experts on both sides of the debate agree about increased support for women. "The problem with women"s reproductive health issues is that they tend to be ignored or exaggerated," Johnston-Robledo said. She added, "We need to find a way to come down in the middle: acknowledge women"s depression but not assume that all women who struggle with the transition to motherhood are depressed."Critics of the bill argue that mental health screenings are notorious for giving false positives. They also contend that increased testing is a bid by pharmaceutical companies to sell more medication to women who do not need it. Some psychologists argue that universal PPD screening would be misdirected because the greatest risk factor for the condition is previous depression, not giving birth. Paula Caplan, a clinical and research psychologist, said, "(We) should be addressing the social factors causing women to be upset after they give birth, not locating the problem within the women."Some proponents of PPD screening say it is not supposed to be used as a diagnostic tool but as a way to identify which patients require further evaluation. According to Time, studies suggest that PPD affects as many as one out of seven women who have recently given birth and that leaving it untreated exposes women and their infants to unwarranted risk. Katherine Wisner, a psychiatrist at the University of Pittsburgh Medical Center, said, "Postpartum depression is not a benign, uncommon thing." She added, "We screen all infants for (the genetic disorder) phenylketonuria, which is extremely rare. Why don"t we screen women for this?" (Elton, Time, 7/20).
Counsellors from around the world will meet to discuss their role in helping people deal with social, cultural, economic and natural challenges at the 2009 International Association for Counselling (IAC) Counference organised by the British Association for Counselling and Psychotherapy (BACP).
Scientists at NOAA"s National Centers for Coastal Ocean Science and the Monterey Bay Aquarium Research Institute (MBARI) have successfully conducted the first remote detection of a harmful algal species and its toxin below the ocean"s surface. The achievement was recently reported in the June issue of Oceanography.
Researchers have identified a potential biological mechanism that could explain why oral contraceptives may be less effective at preventing pregnancy in obese women, as some epidemiological studies have indicated.
A unique study looking at the difference in cardiovascular disease (heart disease and stroke) and life expectancy between people of high and low socio-economic status has found that a person"s IQ may have a role to play.
In Scotland, young men and women (ages 35-44) from socially deprived groups are around six times more likely to die from heart disease than the most affluent individuals in the same age range, according to research published on bmj.com today.
Ben-Gurion University of the Negev (BGU) researchers, in a collaboration with colleagues from the University of Leipzig, Germany, have identified a signaling pathway that is operational in intra-abdominal fat, the fat depot that is most strongly tied to obesity-related morbidity.
Young American-raised Asian and Pacific Islanders (API), who are in the sexual minority, face psychological and social stresses in dealing with their families" values and ancestral cultures that significantly impact the development of their ethnic and sexual identities.
Eliminating polio everywhere will require global cooperation on several fronts, including lowering the cost for poor countries to vaccinate with inactivated polio vaccine (IPV), says a leading global health researcher in the July/August Health Affairs thematic issue on global health.
A team of researchers has discovered an unexpected concentration of a certain isotopic molecule in parts of the stratosphere that could have implications for understanding the carbon cycle and its response to climate change.
New results show that postmenopausal women with breast cancer receiving adjuvant letrozole have better cognitive function than women being treated with tamoxifen. The data, from a recent meeting of the American Society of Clinical Oncology (ASCO), are drawn from a sub-study of the Breast International Group (BIG) 1-98 trial.
Surprising new insights into how a Phase III Alzheimer"s drug might work
Memory lapses that occur with normal aging are a of worry for many who fear Alzheimer"s disease. Now a new Mayo Clinic-led study published in the July 16 issue of the New England Journal of Medicine suggests that the carriers of a common genetic risk factor for Alzheimer"s disease begin to have memory declines in their mid-50s, far earlier than previously thought.
Based on the data presented, the U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) recommended that the combination of DOXIL(R) (doxorubicin HCI liposome injection) and docetaxel did not provide a sufficient benefit-risk profile for first-line treatment of locally advanced or metastatic breast cancer.
Medtronic, Inc. (NYSE:MDT - News) announced completion of enrollment in the TTOP-AF (Tailored Treatment of Permanent Atrial Fibrillation) clinical trial. The study is evaluating the use of the latest radiofrequency (RF) ablation technology, the Medtronic Ablation Frontiers Cardiac Ablation System, for the treatment of continuous atrial fibrillation (AF). A leading advancement from currently available RF ablation tools, the system is comprised of a RF generator (or energy ) and three anatomically shaped mapping and ablation catheters that target three areas of the heart for AF treatment. The system is approved for use in Europe and is under investigational use in the United States.
Health reform may succeed in creating better coverage and access for Americans, but until we reduce the barriers to proper medication adherence, many patients will not experience improved health, according to experts meeting today to discuss the challenges of adherence.
A Massachusetts General Hospital (MGH)-based research team has identified how a chromosomal abnormality known to be associated with acute lymphoblastic leukemia (ALL)- the most common cancer in children- initiates the disease process. In the July issue of Cell Stem Cell, they describe how expression of this mutation in hematopoietic stem cells (HSCs), which usually occurs before birth, leads to the development of leukemia many years later.
The needs of mothers who bottle feed are being neglected, potentially risking the health of their babies, suggests research published ahead of print in the Archives of Disease in Childhood.
CQC publishes national review of NHS child safeguarding
The winner of the chilli cook-off, usually has a key secret ingredient, which is hard to identify. Similarly, many diseases have crucial proteins, which change the dynamics of cells from benign to deadly. New findings from an international collaboration, involving McGill University, the Research Institute of the McGill University Health Centre (MUHC) and the Human Proteome Organisation (HUPO) just made identifying these changes one step easier. Their findings published in Nature Methods, show how to improve protein analysis to tease out relevant potential disease-causing molecules.
"A veteran California lawmaker with ties to the biotechnology industry said she thinks her proposal to protect brand-name biologic makers has enough support to carry in the House Energy and Commerce Committee," Dow Jones Newswires/Wall Street Journal reports. The proposal, by Rep. Anna Eshoo, D-Calif., would protect brand-name biologic products from competition for 12 years. A similar proposal cleared the Senate health committee earlier this week.
"Here"s a little secret you might not know about the health care reform being debated in Washington: Minnesota might not want it," Minnesota Public Radio reports. The state"s congressional delegation is "not sure that the potential cures for the system - requiring everyone to have insurance, expanding Medicare or taxing health benefits - won"t be worse than what currently ails health care." Rep. Collin Peterson, D-Minn., is critical of the additional taxes proposed to help pay for the overhaul. "What they"re talking about doing here is just adding some more gasoline to the fire that"s going to burn down this country. And I"m not going to go along with that," Peterson says.
"The new state budget in Massachusetts eliminates health care coverage for some 30,000 legal immigrants to help close a growing deficit, reversing progress toward universal coverage just as Congress looks to the state as a model for overhauling the nation"s health care system," the New York Times reports. The affected immigrants are permanent residents who have had green cards for less than five years and are insured through the Commonwealth Care program, an insurance program created by the 2006 law that brought near-universal coverage to Massachusetts. The cuts would save around $130 million (Goodnough, 7/14).
Almost half of all artemisinin manufacturers and malaria-endemic countries are "failing to comply" with WHO requirements to sell the treatment in combination with other drugs, which is increasing the risk that malaria parasites will develop resistance to artemsinin, Nature reports. "Of the 69 manufacturers of artemisinin monotherapies that the WHO has identified, 21 have withdrawn monotherapies, and 14 say they intend to comply with the WHO"s recommendations. But the remaining 34 have not yet disclosed their intentions," Nature writes.
A student team in the Virginia Tech College of Engineering is providing the blind with an opportunity many never thought possible: The opportunity to drive.
Two UCSF research papers this week are marking major breakthroughs in the effort to tackle schistosomiasis (bilharzia), a tropical disease that infects more than 200 million people worldwide and causes long-term debilitating illness and occasional paralysis or death.
When we are feeling blue we are told to count our blessings, but according to a study recently published in Psychological Science, counting our money might be a more useful activity. Psychologists Xinyue Zhou, Sun Yat-Sen University, Kathleen D. Vohs, University of Minnesota, and Roy F. Baumeister, Florida State University, investigated the psychological, physical and social impact of money.
NHS clinical teams will have access to data showing their performance against a set of more than 200 indicators of high quality care in the NHS in one place. It is the next phase in the drive to help NHS professionals improve the quality of care they deliver to patients, and will also support providers and commissioners of NHS services.
In the United States, adolescence is a time when many teens become less interested in academics. A new longitudinal study has found that this disengagement is greater for American teens than for Chinese teens.
More than three-quarters of parents would be willing to permit the use of their children"s newborn screening samples for research purposes if their permission were obtained beforehand, a University of Michigan survey shows.
While attending university, men are equally likely as women to have been victims of physical or emotional violence, and that violence is often linked to drinking, according to a new study led by University of British Columbia researcher Elizabeth Saewyc.
For the 11th consecutive year, the University of Pittsburgh Medical Center (UPMC) has been named one of the 100 Most Wired hospitals and health systems in the United States, according to the results of the 2009 survey by Hospitals & Health Networks magazine, the journal of the American Hospital Association. UPMC is one of only five organizations to appear on the list since its inception.
Today, more than 100 future physicians from across the nation will descend on Capitol Hill to lobby on upcoming health care reform legislation.
With entries for the 2009 Wellness Run closing on Sunday 17 May, families and individuals wanting to take part in the popular fitness run are being urged to register now.
Have you seen the commercial for in-office procedures that will make your face wrinkle-free or sculpt your stomach, with no downtime and no scars? Lifestyle Lift, Lunchtime Lift, Thread-Tox, and Smart-Lipo, are just a few of the brand-name surgical procedures being marketed to the public as a cosmetic quick fix with a clever name.
In her third day of confirmation hearings before the Senate Judiciary Committee, Supreme Court nominee Sonia Sotomayor deflected lawmakers" attempts to elicit specific answers on how she would rule on abortion-rights cases and other contentious issues, the Washington Post reports (Goldstein et al., Washington Post, 7/16). As she entered what likely will be the final day of testimony on Thursday, Sotomayor"s confirmation "seemed on track," and Republicans appeared to be "conceding that they had not built the momentum necessary to derail the nomination," according to the New York Times, (Stolberg/Lewis, New York Times, 7/16). Cornyn Questions Abortion-Rights ViewsSen. John Cornyn (R-Texas) asked Sotomayor whether reports that Obama administration officials had sought to elicit her views on abortion were accurate. She responded that she "was asked no question by anyone including the president about my views on any specific legal issue" (Espo/Sherman, AP/Houston Chronicle, 7/15). Cornyn cited comments from George Pavia -- the senior partner at the New York law firm where Sotomayor previously worked -- who stated that he could "guarantee" that she would "be for abortion rights." Sotomayor said, "I have no idea why he"s drawing that conclusion," adding, "If he was talking about the fact that I served on a particular board that promoted equal opportunity for people, the Puerto Rican Legal Defense and Education Fund, then you could talk about that being a liberal instinct, in the sense that I promote equal opportunity in America and the attempts to ensure that." She continued, "But he has not read my jurisprudence for 17 years, I can assure you. He"s a corporate litigator. And my experience with corporate litigators is that they only look at the law when it affects the case before them" (Washington Post, 7/16). Sotomayor added that she "know[s] for a fact that I never spoke to [Pavia] on my views on abortion or my views on any social issue" (Bendavid, "Washington Wire," Wall Street Journal, 7/15). Sotomayor noted that she once ruled to uphold the "global gag rule," also known as the "Mexico City" policy, which barred federal funding of international family planning groups that provide abortion information or services (New York Times, 7/16).Coburn Presses on Hypothetical CasesDuring his questioning, Sen. Tom Coburn (R-Okla.) asked Sotomayor about hypothetical cases related to abortion-rights issues, including if it would be legal if a woman sought an abortion at 38 weeks" gestation if the fetus had spina bifida. Sotomayor said, "I can"t answer that question in the abstract, because I would have to look at what the state of the state"s law was on that question and what the state said with respect to that issue." She continued, "The question is, is the state regulation regulating what a woman does an undue burden? And so I can"t answer your hypothetical, because I can"t look at it as an abstract without knowing what state laws exist on this issue or not. And even if I knew that, I probably couldn"t opine, because I"m sure that situation might well arise before the court" (Holman, "NewsHour with Jim Lehrer," PBS, 7/15). Sotomayor also said that the Supreme Court"s 1992 ruling in Planned Parenthood v. Casey "reaffirmed the core holding of Roe v. Wade that a woman has a constitutional right to terminate her pregnancy in certain cases" (Hirschfeld Davis, AP/Boston Globe, 7/16). She added that the ruling said the court should consider whether any state regulation "has an undue burden on the woman"s constitutional right" (Sherman, AP/Sacramento Bee, 7/15). Coburn also asked whether medical advancements that help premature infants survive might "have any bearing on how we look at" Roe (Savage/Oliphant, Chicago Tribune, 7/16). She said, "I can"t answer that in the abstract," adding, "The question as it would come before me wouldn"t be in the way that you form it as a citizen, it would come to me as a judge" (AP/Houston Chronicle, 7/15).Specter Seeks Clarification on RoeDuring question
Georgetown Policy Report: Long-Term Care in Health Care Reform: Policy Options to Improve Both - Policy - Long-term care reform belongs in health care reform -- "The well-being and financial security of families depend not only on access to affordable medical services, but also on access to affordable, reliable long-term care - the daily assistance and supports that many individuals need because of serious medical conditions or disabilities." This policy brief presents four policy options that merit serious consideration in the current health care reform discussion. ... The first two options would improve long-term care for people with low incomes and limited financial res. These options would modernize Medicaid in important ways, tailoring services better to individual needs and using res more effectively. The third and fourth options aim to strengthen long-term care protections for the broader population; one with better coordination of medical and long-term care for Medicare enrollees; the other by establishing insurance protection for people of all ages and incomes" (Komisar, Tumlinson, Feder, Burke, 7/16). (Note: KHN"s coverage of aging and long term care issues is supported by a grant from The SCAN Foundation.)
Scientists at the Wellcome Trust Sanger Institute have discovered a set of brain proteins responsible for some of the most common and devastating brain diseases. The proteins underlie epilepsy, depression, schizophrenia, bipolar disease, mental retardation and neurodegenerative diseases including Alzheimer"s and Huntington"s diseases.
How well do you know yourself? It"s a question many of us struggle with, as we try to figure out how close we are to who we actually want to be. In a new report in Perspectives on Psychological Science, a journal of the Association for Psychological Science, psychologist Timothy D. Wilson from the University of Virginia describes theories behind self-knowledge (that is, how people form beliefs about themselves), cites challenges psychologists encounter while studying it, and offers ways we can get to know ourselves a little better.
The Daily Trust/allAfrica.com examines food security in Nigeria. Despite its agricultural potential, the "food crisis" in Nigeria "poses a big question as to what is responsible for the insecurity in food production, preservation and storage," according to the newspaper. A government committee recently toured the country in an effort to address some of the problems involved with agricultural production and food insecurity.
US researchers have discovered the molecular mechanisms by which the human body metabolizes selenium, a trace element that plays an essential
The American Society of Hematology (ASH) announces the debut of the Ernest Beutler Lecture and Prize, to be awarded at ASH"s annual meeting in December. The inaugural recipients are Thomas Maniatis, PhD, of Harvard University, and Yuet Wai Kan, MD, of the University of California - San Francisco.
Springer, one of the leading publishers in the fields of science, technology and medicine, has signed a co-publishing agreement with the Association of Food Scientists and Technologists, India (AFST(I)), for one of their publications, the Journal of Food Science and Technology (JFST). Dr. Satish Kulkarni, Head of the Southern Campus at the National Dairy Research Institute in Bangalore and President of AFST(I); Dr. S.G. Prapulla, Deputy Director of the Central Food Technological Research Institute (CFTRI) in Mysore and Honorable Secretary of AFST(I); Dr. William F. Curtis, President of Springer Science+Business Media, LLC; and Sanjiv Goswami, Managing Director of Springer India, signed the agreement at the Southern Campus at the National Dairy Research Institute in Bangalore.
Following Gordon Brown"s meeting at Downing Street with Britain"s top drinks industry executives he called for them to harness their considerable marketing powers to drive for change in social norm and cultural attitudes towards alcohol in the UK. This has resulted in Project "N" - a collaboration of the not inconsiderable res of top companies throughout the UK.
A new study conducted by SANE Australia finds almost half of all Australians still have a very limited understanding of schizophrenia and the everyday reality of living with the illness.
Gliomas are among the most common and most malignant brain tumors. These tumors infiltrate normal brain tissue and grow very rapidly. As a result, surgery can never completely remove the tumor. Now, the neurosurgeons Dr. Darko S. Markovic (Helios Klinikum Berlin-Buch) and Dr. Michael Synowitz (Charit̩) as well as Dr. Rainer Glass and Professor Helmut Kettenmann (both Max Delbr̿ck Center for Molecular Medicine, MDC, Berlin-Buch), have been able to show that glioma cells exploit microglia, the immune cells of the brain, for their expansion (PNAS Early Edition)*.
Those travelling abroad should take seriously advice to pack their condoms and keep their needles to themselves: research published today in the open access journal Retrovirology shows that tourists, travellers and migrants from Greece, Portugal, Serbia and Spain actively export HIV-1 subtype B to other European nations.
The SCAN Foundation released a policy report by Georgetown University researchers presenting four distinct policy options for including long-term care support and services in health care reform. The report comes on the heels of a National Omnibus Survey on Long-Term Care released last week, also from The SCAN Foundation, showing that nearly 80 percent of Americans would be more likely to support a health care reform package that includes improved coverage for long-term care services.
Based on serum bank material, BA profiling was applied in IBD patients and healthy controls which showed that most but not all BA species were decreased to a different extent in CD and UC. BA decreases were highly pronounced in CD patients with surgical interventions in the gut. On the other hand, UC patients with additional liver and gallbladder diseases showed clearly increased levels of those BAs that are synthesized directly in the liver (primary BAs), or subsequently modified by intestinal bacteria (secondary BAs). Furthermore, a marked decrease in the toxic BA lithocholic acid (LCA) was found together with a marked increase in its physiological detoxification product, hyodeoxycholic acid (HDCA), irrespective of the IBD phenotype or clinical manifestation, which showed accelerated detoxification activity in IBD patients. Thus, serum BA profiling might serve as an additional diagnostic tool for IBD characterization and differentiation. In combination with expression profiles of nuclear pregnane X receptor (PXR)-regulated genes, it might allow us to estimate the BA detoxification potential of IBD patients.
WHO publishes its first guidelines on indoor air quality, addressing dampness and mould (WHO guidelines on indoor air quality: dampness and mould. Copenhagen, WHO Regional Office for Europe, 2009 (See Here).
Some people say they never forget a face, a claim now bolstered by psychologists at Harvard University who"ve discovered a group they call "super-recognizers": those who can easily recognize someone they met in passing, even many years later.
Bionovo, Inc. (Nasdaq: BNVI) announced that a study of the gene regulation in multiple cell lines by several of their estrogen receptor beta (ERb) candidates will be published in Public Library of Science One.
Pope Benedict XVI"s fractured wrist. Jill Biden"s shoulder surgery. Various recent injuries sustained by the Boys of Summer. If you need an expert to discuss any of these timely topics, the American Academy of Orthopaedic Surgeons (AAOS) can provide expert s to comment on musculoskeletal injury prevention, diagnosis and treatment.
Respiratory infectious diseases continue to be a huge and rising burden to health-care systems and societies worldwide. Published by Wiley-Blackwell, the latest issue of Respirology includes an invited review series focused on infectious pulmonary diseases.
The following summarizes selected women"s health-related blog entries.~ "Judge Sotomayor Provides Important Testimony on the Constitutional Right to Privacy and Its Application to Reproductive Rights," Marcia Greenberger, Womenstake: "One major line of questions, asked repeatedly throughout the hearings" for President Obama"s Supreme Court nominee Sonia Sotomayor was her "views on the constitutional right to privacy," Greenberger writes, adding, "Given that this right is central to women"s lives, protecting" such "decisions involving whether to bear children ... and having consensual adult sexual relations, it is important to analyze Judge Sotomayor"s answers carefully." According to Greenberger, because Sotomayor "had not ruled directly on the right to privacy as a federal judge, her testimony in this area warrants particular attention." Following questions from senators such as Herb Kohl (D-Wis.), Orrin Hatch (R-Utah) and Dianne Feinstein (D-Calif.), Sotomayor portrayed a "clear agreement with the right to privacy and strong description of the court"s current precedents regarding Roe and women"s health," which "lend[s] further support to the view from her legal record that she would not undermine Roe v. Wade if confirmed to the Supreme Court" (Greenberger, Womenstake, 7/16). ~ "Major Steps Forward for Health Care Reform," Thao Nguyen, Womenstake: Nguyen, outreach manager for the National Women"s Law Center, reports that the health care reform legislation passed by the Senate Health, Education, Labor and Pensions Committee is "particularly important for women because of the critical headway it makes towards women"s ability to secure access to quality, affordable health care throughout their lives." The bill "works towards confronting many of the particular obstacles faced by women in our current health care system," such as banning the "discriminatory" practice of basing insurance premiums on gender, even when maternity benefits are excluded, Nguyen writes. The bill also bans insurance companies from rejecting patients based on medical history, which has prevented many domestic violence survivors and women who have had caesarean sections from obtaining coverage. Nguyen concludes that "the momentum for health care reform could not have come at a more needed time" because women and their families "need quality, affordable and comprehensive health more than ever" (Nguyen, Womenstake, 7/15).~ "Democrats for Life of America Ousts Member Who Supports Contraception," Feministing: Feministing reports that Democrats for Life of America removed Rep. Tim Ryan (D-Ohio) from its advisory board because he supports efforts to improve access to contraception. According to Ryan, he was dismissed from the board after four years after attempting to persuade the group to support contraceptive use as a way to avoid unintended pregnancies. According to the blog, "This is why we call anti-choicers "anti-choice": because they"re not just about making abortion illegal." It adds, "They don"t want women to have access to contraception either -- something that 98% of American women will use at some point in their lives" (Feministing, 7/15). ~ "Umpires, Perspective and the Supreme Court," Jim Wallis, Sojourners" "God"s Politics": "During his opening remarks for his own confirmation hearing in 2005, Chief Justice [John] Roberts made" an analogy between judges and umpires "that has gotten a lot of play in the media and has already been used quite a few times during" Sotomayor"s confirmation hearing, Wallis writes. He adds that "nothing in the world would frustrate me more than an umpire who would call the game differently based upon the color of the jersey that" players were wearing. "But I haven"t seen that happen," Wallis writes, adding, "In fact, the biggest problem we face isn"t an umpire that has favored one team over the other, but umpires who make mistakes in their rulings and judgment because of their lack of perspective." He adds that Sen. Jeff Sessions (R-Ala.) and "others w
A new study finds more veterans being diagnosed with mental health issues. The study was posted Thursday on the web site of The American Journal of Public Health.
California cuts back on health insurance for children, while New Hampshire expands state insurance to young adults. Meanwhile, a regional health commission in Missouri hopes to help the uninsured, and an Iowa report concludes that minorities face discrimination in the health care system.
Why are some people smarter than others? In a new article in Current Directions in Psychological Science, a journal of the Association for Psychological Science, Eduardo Mercado III from the University at Buffalo, The State University of New York, describes how certain aspects of brain structure and function help determine how easily we learn new things, and how learning capacity contributes to individual differences in intelligence.
Bed bugs, known scientifically as Cimex lectularius (Cimicidae) are small wingless insects that feed by hematophagy - exclusively on the blood of warm blooded-animals. As we are warm-blooded animals we are ideal hosts for them. Over millions of years bed bugs have evolved as nest parasites - inhabiting the nests of birds and the roosts of bats. Some of them have learnt to adapt to the human environment and live in our nests, i.e. our homes, and more specifically, our beds. Newborns, called hatchlings or nymphs, are tiny, about the size of a poppy seed, while adults grow to about ÂÜ of an inch long. Their shape is oval and flattened. Both nymphs, eggs and adults are visible to the naked eye.
The incidence of obesity among US blacks is higher than among Hispanics and non-Hispanic whites, reports the Centers for Disease Control and
A third of Western Australian GPs aged 45-65 years plan to retire early, potentially deepening Australia"s medical workforce shortage, according to research published in this year"s General Practice edition of the Medical Journal of Australia.
"Where care lodges, sleep will never lie," says Shakespeare in Romeo and Juliet.
Diabetes patients taking NovoLog® (insulin aspart [rDNA origin] injection) can now use the insulin in their pump for up to six days following the U.S. Food and Drug Administration (FDA) approval of a labeling change, diabetes care company Novo Nordisk announced today.[i] The previous label allowed for NovoLog® to be stored in the pump reservoir for two days. This makes NovoLog® the first and only rapid-acting insulin with this extended in-use time.
American Medical Association sent a letter to House leaders supporting H.R. 3200, "America"s Affordable Health Choices Act of 2009."
Data from two presentations highlighting the use of Perforomist® (formoterol fumarate) Inhalation Solution in moderate to severe chronic obstructive pulmonary disease (COPD) patients were featured at the International Conference of the American Thoracic Society in San Diego. In one analysis, use of Perforomist Inhalation Solution, when added to maintenance tiotropium, resulted in improved pulmonary function, dyspnea (shortness of breath) and rescue medication use versus treatment with tiotropium alone. In a second study, patient satisfaction increased in those treated with Perforomist Inhalation Solution twice daily compared with ipratropium/albuterol metered-dose inhaler (MDI) four times daily.
A study of oyster reefs in a once-pristine California coastal estuary found them devastated by invasive Atlantic Coast crabs and snails, providing new evidence of the consequences when human activities move species beyond their natural borders.
The Honourable Leona Aglukkaq, Minister of Health, today highlighted some of the important work the Government of Canada is doing to protect and support the health and safety of Canadians.
US Oncology, Inc. today announced that US Oncology Research will participate in the BiPar Sciences" Phase III, Multi-center, Open-Label, Randomized Trial of Gemcitabine/Carboplatin (G/C), with or without BSI-201, in patients with Estrogen Receptor (ER), Progesterone Receptor (PR), and HER2-negative metastatic breast cancer.
Five organizations representing the nation"s experts in infectious diseases medicine, infection prevention in healthcare settings, and public health and disease prevention announced their support for a provision requiring national reporting of healthcare-associated infection (HAI) rates, which is contained within the healthcare reform bill introduced by leaders of the U.S. House of Representatives.
University of Medicine and Dentistry of New Jersey (UMDNJ) researchers have discovered a therapeutic target that, when manipulated, may slow the progression of or halt Parkinson"s disease, a debilitating neurodegenerative disorder that affects an estimated one million people in the U.S.
Many countries worldwide are digitizing patients" medical records. In the
An FDA-approved drug used for preventing recurrence of breast cancer shows promise in fighting life-threatening fungal infections common in immune-compromised patients, such as infants born prematurely and patients with cancer. Some scientists suspected that tamoxifen has antifungal properties; now new research from the University of Rochester Medical Center shows that it actually kills fungus cells and stops them from causing disease.
The US Food and Drug Administration (FDA) announced yesterday that it has approved a vaccine for 2009-2010 seasonal influenza in the United
It is estimated that 1.4 billion people live in extreme poverty, on less than $2 a day. In 2000, 189 nations declared that they would "free all men, women, and children from the abject and dehumanizing conditions of extreme poverty". These nations signed up to Millennium Development Goals (MDGs) to combat poverty by 2015. To help meet these complex challenges and "make poverty history" more knowledge and evidence is needed. A launch event Wednesday 22nd July 2009 at the Department for International Development (DFID) marks a new phase of research collaboration between the Economic and Social Research Council (ESRC) and DFID which will provide more robust social science research to address poverty alleviation amongst the poorest countries and peoples of the world.
Three U.S. hospitals were recognized today for their leadership and innovation in quality, safety and commitment to patient care. The 2009 American Hospital Association-McKesson Quest for Quality Prize® was awarded to Bronson Methodist Hospital in Kalamazoo, Mich., which will receive $75,000. Bronson Methodist Hospital, a 380-bed hospital serving patients and communities in southwest Michigan and northern Indiana, was selected by a multi-disciplinary committee of health care quality and patient safety experts based on its culture of quality and efforts to achieve the Institute of Medicine"s six quality aims for health care. Beth Israel Deaconess Medical Center in Boston was honored as the finalist and will receive $12,500. Duke University Hospital in Durham, N.C., received the Citation of Merit.
HIV Susceptibility Testing Increases Patient Survival