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Home-Loving Rats: Finding Significant For Tracking Spread Of Rodent-Borne Diseases
In the rat race of life, one thing is certain: there"s no place like home.
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Daily Women's Health Policy Report Summarizes Studies Examining Ovarian Cancer
The following summarizes recent research related to ovarian cancer.~ Early periods linked to lower survival: Women who start menstruating at an early age or experience more menstrual cycles over their lifetimes appear to have a lower chance of surviving ovarian cancer, according to a study published this month in the journal Cancer Epidemiology, Biomarkers, and Prevention, Reuters reports. For the study, researcher Cheryl Robbins and colleagues analyzed the medical data of 410 ovarian cancer patients who participated in the Cancer and Steroid Hormone study between 1980 and 1982. The analysis found that the women who had their first period before age 12 had a 51% greater risk of dying than the women who began menstruating at age 14 or older. The women who had the highest number of lifetime menstrual cycles had a 67% greater risk of dying during follow-up than the women with the lowest number of cycles (Reuters, 7/24).~ Lung cancer risk higher for women after hysterectomy with ovary removal: Women who have had hysterectomies in which their uterus and both ovaries are removed to prevent ovarian cancer appear to have a higher risk for developing lung cancer, according to researchers at the University of Montreal, the New York Times reports. The researchers discovered the connection while looking for links between lung cancer and hormones for a study published in May in the International Journal of Cancer. Although they did not find a relationship between lung cancer risk and hormonal factors such as menstruation patterns, child-bearing or breastfeeding, the researchers found that women who had medically induced menopause had 1.92 times greater risk of developing lung cancer than women who had natural menopause (Caryn Rabin, New York Times, 7/24).~ Small tumors present for years before detection: Minute-sized ovarian tumors form and remain in the Fallopian tubes for an average of four years before they grow large enough to be detected, which might suggest why ovarian cancer frequently is diagnosed in its later stages, according to a study published in the journal PLoS Medicine, Reuters reports. For the study, lead researcher Patrick Brown of Stanford University and the Howard Hughes Medical Institute and colleagues analyzed the tumors of women whose Fallopian tubes and ovaries were removed because they had family histories of and genetic risk for ovarian cancer. They found small tumors -- most less than three millimeters in diameter -- that previously had not been detected in the women. In a statement, Brown said, "There is a long window of opportunity for potentially lifesaving early detection of this disease, but the tumor spreads while it is still much too small to be detected by any of the tests that have been developed or proposed to date." According to Reuters, blood tests for the compound called CA-125 may help guide therapy but do not indicate whether a woman has a tumor (Reuters, 7/28).
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Synosia Therapeutics Begins Phase I Trial Of A New Generation Treatment For Cognitive Impairment In Alzheimer's Disease And Schizophrenia
Synosia Therapeutics announced today that it has started a Phase I clinical trial of SYN-120, its new generation 5-HT6 antagonist under development for the treatment of cognitive impairment associated with Alzheimer"s and schizophrenia. The study will assess the safety and tolerability of single ascending doses of SYN-120 in healthy volunteers.
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Schumer Preparing Strong Public Plan Option

Sen. Charles Schumer, D-N.Y., a member of the key Senate Finance Committee and advocate for a government-run health insurance plan, said yesterday he would abandon all other possible compromises in favor of immediately creating a public plan that "would operate on "a level playing field" with private insurers," CongressDaily reports. Other proposals have included a plan that would establish health insurance co-ops with government seed money or "trigger" the creation of a public plan only if private insurers fail to meet certain targets for containing costs and improving access. Schumer"s office said he was preparing an amendment to the Finance Committee"s bill, which is expected as early as next week, suggesting that the bill will include one of the other alternatives designed to seek bipartisan compromise. "Schumer"s announcement is a potential blow to bipartisan efforts on the Finance Committee, where some Republicans prefer, if not fully support, the co-op proposal," CongressDaily reports (Edney, 7/1). It"s not just Republicans who may be unsettled by the push for the public plan. Sen. Joe Lieberman, I-Conn., a four-term senator who caucuses with the Democrats, told home- state reporters this week, "If we create a public option, the public is going to end up paying for it. That"s a cost we can"t take on," the New Haven Independent reports (Bass, 7/1). Some liberal Democrats are also troubled - that the talked-about public plan compromises, including Schumer"s, are too weak. "We haven"t yet applied enough pressure to get done what has to be done," David Himmelstein, a single-payer advocate and cofounder of Physicians for a National Health Program, told the Christian Science Monitor. Single-payer reform has not gained traction in either the House or Senate, but some liberal congressmen have stated that it is their preference. Rep. John Conyers, D-Mich., for instance, introduced a bill to create one such plan (Francis, 6/1). This information was reprinted from kaiserhealthnews.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Health Policy Report, search the archives and sign up for email delivery at kaiserhealthnews.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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