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Understanding Of Antidepressant Drugs Enhanced By New Mouse Model Of Depression/Anxiety
A recent study finds that the antidepressant effects of drugs like Prozac involve both neurogenesis-dependent and -independent mechanisms, a finding that may lead to development of better treatments for depression and anxiety. The research, published by Cell Press in the May 28th issue of the journal Neuron, utilizes a new experimental mouse model of depression/anxiety that is the first to permit simultaneous examination of multiple effects of antidepressant treatment in the same animal.
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International Workshop Assesses Revisions Aimed At The Purity, Quality Of Blood Thinner
Continuing to help ensure the identity, purity and quality of heparin, the U.S. Pharmacopeial (USP) Convention has revised written and physical standards for the widely used blood thinner. In February, USP released updated heparin standards at the request of the Food and Drug Administration (FDA) in response to the 2008 public health crisis in which more than 200 people died as a result of heparin adulterated for economic gain. A second phase of revisions is reflected in the newly posted standards. These developments and new information about heparin were discussed by scientists and regulators at the third International Heparin Workshop held at USP headquarters in Rockville, Maryland, July 27.
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VeroScience Presents Data On Newly FDA Approved Drug Cycloset At American Diabetes Association Annual Scientific Sessions
VeroScience, in collaboration with S2 Therapeutics, announced the presentation of clinical and preclinical data at the American Diabetes Association (ADA) 69th Scientific Sessions on Cycloset, a novel treatment for patients with Type 2 diabetes. FDA-approved in May 2009, Cycloset is the first therapy directly targeting the body"s dopamine activity to improve glycemic control. It is also the only drug to be approved subsequent to the FDA"s new guidelines that require studies demonstrating that diabetes drugs do not increase cardiovascular risk.
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New Technology At Great Ormond Street Hospital Is Aiding Faster Emergency Referrals To Its Specialist Paediatricians, England

Thanks to the introduction of an innovative IT system at the Children"s Acute Transport Service (CATS) hosted at Great Ormond Street Hospital for Children NHS Trust (GOSH), referring hospitals can now share perfect quality medical data on emergency patients more quickly and securely than ever before. The product, named CATS-i, has been co-developed by software manufacturer Cimar UK and GOSH. Over the last 12 months, the technology has been trialled by the CATS team at GOSH. CATS is a paediatric intensive care retrieval service for the North Thames and East Anglia region. The team provides telephone advice and sends a specialist team to safely bring sick children back to the intensive care unit at GOSH and other tertiary centres. More than 50 hospitals in and around London regularly refer patients to the service. Dr Padmanabhan Ramnarayan, consultant for the CATS team at GOSH and a co-inventor of CATS-i explains. "Previously, we simply relied on telephone conversations with referring clinicians and relatively low quality radiology (X-rays, CT scans) to make a quick assessment about a diagnosis. Radiology data would often be sent via courier, which loses us valuable time. In an emergency situation, every second counts and this is where CATS-i offers us a clear advantage. For example, in a recent case, a boy had been in a road traffic accident outside London and with the help of CATS-i we quickly determined from his medical data that he had a windpipe injury. The child was brought to GOSH by helicopter and was given life-saving treatment by our tracheal team." CATS-i offers a unique web-transmission service which allows pristine medical images to be transmitted from any hospital in the UK to remote recipients anywhere, securely, reliably and fast via an internet browser. The images are losslessly compressed (i.e. retaining absolute image quality), secure and encrypted throughout, so patient data confidentiality is not compromised. The user cannot send anything until they have a secure token issued by the CATS office each time. The CATS-i project was commended in NHS Innovations London"s Innovator Awards 2008. NHS Innovations London has recently brokered an agreement between GOSH and Cimar UK to distribute the co developed service. Dr Ramnarayan continues: "We"re very excited about this product being available commercially. It"s satisfying to see something that we"ve worked so hard on being made available to others so that they can improve the service to their patients". A prime-time BBC 1 series following the work of the CATS team is due to be screened later this year. NHS Innovations London


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