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AARP Executive Vice President Nancy LeaMond released
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Evaluating The ADHD Medication VYVANSE CII Demonstrated No Change In Pharmacokinetic Profile Of VYVANSE When Coadministered With Prilosec OTC 40 Mg
Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announced results of a study showing that coadministration of the ADHD medication VYVANSE® (lisdexamfetamine dimesylate) CII with the proton pump inhibitor (PPI) Prilosec OTC® 40 mg (20 mg X 2), did not alter the median time it took for maximum plasma concentration of d-amphetamine to be reached in the subjects evaluated. In the same study, coadministration of Prilosec OTC with ADDERALL XR resulted in a nearly 45 percent reduction in the median time to reach maximum plasma concentrations of amphetamine, the active medication. Other pharmacokinetic parameters (maximum plasma concentration and area under curve) of active medication were not altered for either VYVANSE or ADDERALL XR when coadministered with Prilosec OTC. This study, which is the first to evaluate the pharmacokinetics of VYVANSE and ADDERALL XR taken alone and with Prilosec OTC 40 mg, was recently presented at the International Congress on Clinical Pharmacy, co-sponsored by the American College of Clinical Pharmacy (ACCP), in Orlando, FL.
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New Guide Explains Prosecutions For HIV Transmission
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Insomnia May Be Treated Effectively By Meditation

Meditation may be an effective behavioral intervention in the treatment of insomnia, according to a research abstract presented at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies Results indicate that patients saw improvements in subjective sleep quality and sleep diary parameters while practicing meditation. Sleep latency, total sleep time, total wake time, wake after sleep onset, sleep efficiency, sleep quality and depression improved in patients who used meditation. According to principal investigator Ramadevi Gourineni, MD, director of the insomnia program at Northwestern Memorial Hospital in Evanston, Ill., insomnia is believed to be a 24-hour problem of hyperarousal, and elevated measures of arousals are seen throughout the day. "Results of the study show that teaching deep relaxation techniques during the daytime can help improve sleep at night," said Gourineni. The study gathered data from 11 healthy subjects between the ages of 25 and 45 years with chronic primary insomnia. Participants were divided into two intervention groups for two months: Kriya Yoga (a form of meditation that is used to focus internalized attention and has been shown to reduce measures of arousal) and health education. Subjective measures of sleep and depression were collected at baseline and after the two-month period. Both groups received sleep hygiene education; members of the health education group also received information about health-related topics and how to improve health through exercise, nutrition, weight loss and stress management. Abstract Title: Effects of Meditation on Sleep in Individuals with Chronic Insomnia Presentation Date: Tuesday, June 9 Category: Insomnia Abstract ID: 0874 Kelly Wagner American Academy of Sleep Medicine


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