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Researchers Profile Gene Activity In Acutely Ill Idiopathic Pulmonary Fibrosis Patients
New research may help doctors pinpoint when patients with idiopathic pulmonary fibrosis (IPF) are becoming dangerously ill. The findings may also point the way to interventions that could sustain the lives of IPF patients until life-saving transplants could be performed.
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Working Memory May Be Improved By Short Stressful Events
Experiencing chronic stress day after day can produce wear and tear on the body physically and mentally, and can have a detrimental effect on learning and emotion. However, acute stress -- a short stressful incident -- may enhance learning and memory.
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Southampton Surgeons Honoured For Developing Keyhole Lung Cancer Surgery In The UK
Two Southampton surgeons who contributed to the development of keyhole surgery to treat early stage lung cancer have been internationally commended for their work.
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Improving The Biomarker Pipeline For Early Cancer Detection

Several statistical and biological issues need to be addressed in order to improve biomarker identification for early detection of cancer, according to a commentary published online July 2 in the Journal of the National Cancer Institute. The biomarker pipeline to develop and evaluate cancer screening tests includes the identification of promising biomarkers to detect cancers early and the initial and definitive evaluation of biomarkers for cancer screening. In the commentary, Stuart G. Baker, ScD, of the National Cancer Institute in Bethesda, Md., discusses the various ways to improve this pipeline, including the need for more frequent specimen collection to help identify promising biomarkers and the use of the paired availability design, in which data are collected on the number of interval cases associated with screening in time periods before and after the introduction of the new biomarker test. "ò€¦[S]ome important design and analysis considerations related to this biomarker pipeline have been underappreciated, insufficiently disseminated, or not previously discussed," the author writes. "By taking these considerations into account, researchers can improve this biomarker pipeline." Steve Graff Journal of the National Cancer Institute


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