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Senate Republicans Ask For More Background On Supreme Court Nominee Sotomayor
Senate Judiciary Committee Republicans on Wednesday sent a letter to Supreme Court nominee Sonia Sotomayor requesting additional background information to supplement a committee questionnaire, CQ Today reports. The Republicans said that Democrats are rushing the nomination process by scheduling Sotomayor"s confirmation hearing to begin July 13 and that they need more information on the nominee. According to CQ Today, Democrats are unlikely to budge from their determination to confirm Sotomayor before the Aug. 7 recess, although Republicans might convince Leahy to postpone the hearing for a week in exchange for a GOP pledge not to delay a committee vote on Sotomayor for a week, as allowed under the panel"s rules (Perine, CQ Today, 6/10). Among their requests, Republicans asked that Sotomayor provide copies of the Yale Law Journal, for which she served as an editor, and that she elaborate upon her role with the Puerto Rican Legal Defense and Education Fund. White House spokesperson Ben LaBolt said that the Obama administration has made clear that it plans to provide additional information but that it has presented most of the information quickly to allow the Senate to begin its review (Herszenhorn, "The Caucus," New York Times, 6/10). Judiciary Committee ranking member Jeff Sessions (R-Ala.) said that the information requested is not "little itty-bitty matters" but "important" components of Sotomayor"s background. He added, "If we"re going to move forward in a record-breaking time frame, the least we can expect is complete and full answers to these questions." Sen. Orrin Hatch (R-Utah), a senior member on the committee, said there is "a lot of irritation and discomfort" among Republicans "about the way it"s being handled." He added that he does not think Republicans want to filibuster the nomination but implied that they might use procedural tools to slow the process (CQ Today, 6/10).
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FDA Classifies Previously Announced Medtronic Physician Advisory On Small Subset Of Kappa And Sigma Pacemakers As Class I Recall
Medtronic, Inc. (NYSE: MDT) announced the U.S. Food and Drug Administration (FDA) has classified Medtronic"s previously announced physician advisory about a small subset of Kappa® and Sigma® series pacemakers, identified at increased susceptibility for separation of bonded interconnect wires from the electronic circuit, as a Class I recall. Notification to U.S. FDA, physicians and patients began May 18, 2009. As of the date of this news release, more than 95 percent of physicians following affected devices in the United States have confirmed receipt of the notification. The FDA"s classification of Medtronic"s Important Patient Safety Information does not alter the patient management recommendations already provided in the May 2009 letter, and physicians need not take any new action.
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HUD To Distribute $310M In Housing Assistance Grants For People Living With HIV/AIDS
The U.S. Department of Housing and Urban Development (HUD) on Wednesday announced that it will provide several housing assistance grants to help low-income families living with HIV/AIDS, the Boston Globe reports (7/23). "A record $310 million will assist 58,000 U.S. households annually, officials said," KITV.com reports. The grants were distributed based on the number of AIDS cases reported nationwide. The Gregory House Programs of Honolulu, a nonprofit that provides housing assistance, substance use and other services, will receive $1.3 million (KITV.com, 7/22). The Frannie Peabody Center in Portland, Maine, will receive $1.3 million; the city of Portland will receive $1.4; New Hampshire will receive over $716,000; and the Burlington Housing Authority in Vermont will receive over $392,000, the Globe reports (7/23).
Nutrition

Can Omega 3 Fatty Acids Prevent Depression In Coronary Heart Disease?

Depression is an established risk factor for the development of coronary heart disease (CHD) in healthy patients and for adverse cardiovascular outcomes in patients with existing CHD. Dietary factors resulting in lower levels of omega 3 fatty acids not only increase CHD risk, but may also be involved in the pathophysiology of depression. The investigators measured red blood cell levels of two omega 3 fatty acids, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), and assessed depressive symptoms in a cross-sectional study of 987 adults with CHD. Omega 3 fatty acids were blindly measured in fasting venous blood samples using capillary gas chromatography to measure the fatty acid composition of red blood cell membranes. Red blood cell levels of EPA and DHA are presented as a percentage composition of total fatty acid methyl esters. The investigators assessed current depression using the 9-item Patient Health Questionnaire. They evaluated the association between omega 3 fatty acid levels and depressive symptoms as continuous variables using linear regression. The investigators also examined the association of omeg 3 fatty acid tertiles with depression as a dichotomous variable using X2 analysis and logistic regression. All statistical tests were two-sided, and p4.3% of total blood fatty acids; p for trend = 0.004). Each unit decrease in EPA + DHA was inversely associated with depressive symptoms as a continuous variable, and these associations persisted after adjustment for age, sex and race. Similarly, each SD decrease in EPA + DHA was associated with significantly greater odds of depression as a dichotomous variable (Patient Health Questionnaire score >10). However, in both analyses, omega 3 fatty acid levels were no longer associated with depression after adjustment for education and household income level. This study extends this existing literature by finding a strong association between low omeg 3 fatty acids and depression in outpatients with stable CHD, a population distinct from sicker, hospitalized patients with acute coronary syndrome. In addition, the investigators examined the role of several important potential confounders and measured erythrocyte membrane levels of fatty acids rather than using less accurate serum measurements or dietary questionnaires. However, the cross-sectional nature of this study precluded the investigators from making any definitive comments on causality. Additionally, the cohort participants were mostly older, urban men and thus are not entirely reflective of the general population. To better understand the potential efficacy of omeg 3 fatty acid supplementation for improving depressive symptoms in patients with CHD, future studies should carefully consider the role of socioeconomic status (SES) in this association. Psychotherapy and Psychosomatics


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