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Office Of The National Alzheimer's Project Act Will Produce A National Strategic Plan For Alzheimer's Research, Care, And Related Supportive Services
U.S. Senators Mel Martinez (R-FL) and Evan Bayh (D-IN) introduced a measure to create a collaborated system for researching, treating and eliminating Alzheimer"s disease. The proposal will create an Office of the National Alzheimer"s Project within the White House, and will coordinate all research, clinical care and service toward the prevention, care, and cure of Alzheimer"s. This office will produce a national strategic plan to help assure that the millions of Americans who now have Alzheimer"s and the millions of potentially at-risk Americans will have a coordinated effort to target the 6th leading cause of death in the United States.
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Role Of MRI In Targeting Prostate Cancer In Patients With Previous Negative Biopsies And Elevated Prostate-Specific Antigen Levels
UroToday.com - In this recent review we highlight the important role of MRI in assisting in the detection of prostate cancer (CaP) in men with previous negative biopsies and elevated prostate-specific antigen levels. [1]
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Estrogen Getting Cool Reception From Dermatologists For Mixed Results In Improving Appearance Of Skin
For many women, hormone replacement therapy (HRT) can alleviate the physical symptoms associated with the change of life. But despite the initial hype generated by post-menopausal women who noticed a marked improvement in their skin"s appearance while on HRT, dermatologists argue that scientific studies of estrogen do not show definitive improvements for skin rejuvenation of photodamaged skin and the potential risks when used long-term outweigh any potential skin benefits.
Diagnostics

Bone Marrow Cell Therapy May Be Beneficial For Patients With Ischemic Heart Disease

The injection of bone marrow cells into the heart of patients with chronic myocardial ischemia (reduced blood flow to some areas of the heart) was associated with modest improvements in blood flow and function of the left ventricle, according to a study in the May 20 issue of JAMA. Bone marrow cell therapy is currently being investigated as a new therapeutic option for patients with ischemic heart disease. Two small-sized studies assessed the effect of this therapy in patients with chronic myocardial ischemia, but with varying results, according to background information in the article. Jan van Ramshorst, M.D., of Leiden University Medical Center, the Netherlands, and colleagues assessed the effect of intramyocardial (within the heart wall) bone marrow cell injection on myocardial perfusion (the flow of blood to the heart muscle) and left ventricular (LV) function in patients with chronic ischemia who were not eligible for conventional treatment. The trial included 50 patients (average age, 64 years; 43 men), who were randomized to receive about 8 injections of either bone marrow cells or placebo solution. At 3-month follow-up, when the two groups were compared, the improvement in summed stress score (a measure of myocardial perfusion) was significantly greater in the bone marrow-cell treated patients as compared with placebo-treated patients. Magnetic resonance imaging indicated that the absolute increase in left ventricular ejection fraction (LVEF; a measure of how well the left ventricle of the heart pumps with each contraction) was significantly larger in bone marrow cell-treated patients. A quality-of-life score increased at 3 and 6 months in bone marrow cell-treated patients, compared with a smaller increase in the placebo group. There was also greater improvement in exercise capacity in the bone marrow cell group. "In summary, the results of this randomized, double-blind, placebo-controlled trial demonstrate that intramyocardial bone marrow cell injection in patients with chronic ischemia is associated with significant improvements in anginal symptoms, myocardial perfusion, and LV function," the authors write. JAMA 2009;301[19]:1997-2004. JAMA


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