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Embryo Movement Stimulates Joint Formation
A new study uncovers a molecular mechanism that explains why joints fail to develop in embryos with paralyzed limbs. The research, published by Cell Press in the May issue of the journal Developmental Cell, answers a longstanding question about the influence of muscle activity on developing joints and underscores the critical contribution of movement to regulation of a signaling pathway that is important during development and beyond.
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HIV Awareness, Testing Efforts In Cincinnati, Northern Kentucky Target Black Community, Others
Religious leaders, health care workers, community organizations and government agencies in Greater Cincinnati and Northern Kentucky have begun a number of HIV and sexual health awareness efforts that encourage members of the black community, and others, to get tested, the Cincinnati Enquirer reports. To increase the number of people being tested, the Northern Kentucky Health Department is providing HIV testing in people"s homes and the Cincinnati Health Department, along with other organizations, is conducting HIV testing in bars and clubs. Cincinnati also is a pilot site for the Black AIDS Institute"s "Test One Million" campaign. Separately, the Ohio Department of Rehabilitation and Corrections is nearing the end of a two-year pilot program in one prison that is testing inmates for HIV and other sexually transmitted infections upon their release. Other efforts in the states include condom distribution and HIV education (O"Farrell, Cincinnati Enquirer, 6/5).
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Group Files Petition Over Enforcement Of Regulations In Adult Film Industry To Prevent Sexually Transmitted Diseases
The AIDS Healthcare Foundation last week filed a petition in Los Angeles County Superior Court asking "the court to order the Los Angeles County Department of Public Health to enforce regulations that require condom use in adult-film production or take other reasonable steps to stem the spread of disease," the Los Angeles Times reports (Yoshino, 7/17). In the petition, "the group claims that in the month since an actress tested positive for HIV, the county Department of Public Health has done little to address what it considers to be a serious health threat" (AP/San Jose Mercury News, 7/16). In a statement released last week, the department, said, "The county continues to strongly support state legislation and the regulatory role of the [California Division of Occupational Safety and Health] as the most appropriate means to regulate the practices in the adult-film industry that expose performers to unnecessary and preventable occupational risks of acquiring and transmitting these diseases," adding, "The department does not believe that litigation is the best means to deal with this issue" (Yoshino, 7/17).
Medical Devices

Appeal For Cancer Patients To Trial New Nail Damage Remedy

The search is on for fifty cancer patients undergoing chemo or radiotherapy to trial an innovative, natural cosmetic product, Evonail, aimed at reversing the damage done to cracked or broken nails during anti-cancer treatments. Evolife"s full range of support care products, including Evonail, are regularly used in France and in over 16 countries in the world, but they have only recently been launched in the UK through the http://www.feelbetterduringchemo.com website, operated by Feel Better Ltd. In 2006, a study showed that 20 to 25% of nail alterations were diagnosed as side effects of chemotherapy. Cracked and brittle nails can be a painful and debilitating side-effect of cancer and radiotherapy treatment making simple tasks like turning the page of a magazine excruciating. Anyone wanting to volunteer for the trial simply needs to send an email to contact@feelbetterduringchemo.com. Anti-cancer treatments can cause nails to become dehydrated, often making them become darkened, yellow, brittle or cracked. They may also develop vertical lines or bands. Evonail helps restore the nails" moisture levels, making them stronger whilst reducing cracks and flakes. Speaking from the ASCO World Oncology Congress in Orlando where Evolife was being launched in the US, Charles Felgate, joint Managing Director of Feel Better Ltd, said: "Up until now cancer patients have had to suffer in silence with little relief from the distressing side effects of chemo and radiotherapy. Now Evonail brings real relief to people who find the simplest of tasks painful because of their brittle nails." The effectiveness of the product on chemotherapy patients was discovered when Dr Geraldine Reynaert, a French dermatologist, was transferred to an oncology clinic in Marseille. She noticed that nail problems caused by cancer treatments were similar to those suffered by the psoriasis patients she had treated previously. She decided therefore to try out the Evaux Laboratories product she had been using. Dr Reynaert said: "In light of the outstanding results achieved, I informed the Evaux Laboratoires research and development team who began to work on a specifically adapted Totum Lithium formula* which eventually became EVONAIL. I then tested this product, successfully, on numerous patients." With scientific papers from the "Journal of Neuro-Oncology" backing up her findings, Dr Raeynart has continued to help Evolife Laboratoires with their research into various topics relating to the different forms of cutaneous and cutaneo-mucous side effects in chemotherapy and radiotherapy. She has actively taken part in the development of the 10 specific EVOLIFE products that are now available in the UK." Dr Reynaert isn"t the only doctor to use the product. Dr Radu Vanica, from the Medical Oncology Department of Argenteuil Hospital, Paris, said: "We have used Evonail on patients presenting side effects on their nails after having undergone anti-tumour treatments. The efficiency of the product and the visible improvements were remarkable." Dr Sylvie Delanian from the Hospital Saint Louis in Paris added: "Please allow me to express my sincere gratitude for the Evolife products that are used to treat cancer patients undergoing chemotherapy, particularly Evonail. Patients being treated with breast, prostate and lung cancer were happy to be rid of the handicap affecting their finger and toe nails." The Evolife product range, available exclusively from Feel Better Ltd, has been designed to make unpleasant cutaneous side effects of chemo and radiotherapy treatments more bearable. The collection includes gels, sprays and creams, and is already used by a number of leading oncologists and cancer treatment centres in France and worldwide, with remarkable results. Evolife provides solutions to problems that previously had few answers. These include cracked and broken nails (Evonail); flaking and broken skin (Evoskin); mouth ulcers (Evomucy), dry mouth (Evodry) and body odour (Evodeo), to name but a few. * Totum Lithium describes the unique composition of Evaux-les-Bains spring water Feel Better Ltd


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